Cerebral blood flow predicts differential neurotransmitter activity
نویسندگان
چکیده
منابع مشابه
Four facets of a single brain: behaviour, cerebral blood flow/metabolism, neuronal activity and neurotransmitter dynamics.
Is functional neuroimaging a royal way to understand brain function or is it a new phrenology without an exact understanding what we measure? After two decades of imaging revolution, more and more authors ask this question. Brain functions are multidimensional, which can be approached from the point of (1) behavioural measures, (2) brain activation as reflected by blood flow and metabolic chang...
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BACKGROUND AND PURPOSE We sought to study the role of MRI-derived cerebral blood flow (CBF) measurements for the prediction of lesion development in acute stroke patients. METHODS Thirty-two patients were treated with tissue plasminogen activator. Diffusion-weighted (DWI) and perfusion-weighted MRI, T2-weighted imaging, and MR angiography were performed before treatment (2.8+/-0.9 hours after...
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Cerebral arteries are abundantly innervated by sympathetic fibers, but their influence on cerebral vessels was held unimportant for almost a century (2, 20). Whether there is sympathetic influence on cerebral blood flow (CBF) is important in the management of hypotensive patients. If there is no -adrenergic influence on CBF, a low mean arterial pressure (MAP) can be increased to the cerebral au...
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BACKGROUND AND PURPOSE We found age-related vulnerability to cerebral ischemia in the hippocampus and striatum in spontaneously hypertensive rats. Further study revealed that ischemia-induced release of hippocampal taurine, an inhibitory amino acid, was reduced by 40% in aged rats compared with adult rats, which suggested an impaired inhibitory function against excitotoxicity in aged rats. The ...
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Rapid vascular resistance adjustments in the brain and in the circle of Willis have been continuously measured and enhanced by signal averaging methods. Naftidrofuryl, a drug chemically similar to local anesthetics and to beta adrenergic blocking agents, increases local CBF by reducing resistance in brain and in extracerebral supply arteries. It has also been reported to affect brain metabolism...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-22444-0